The long-term goal of our research is to understand the large scale protein conformational changes that occur en route to protein aggregation– a protein’s aggregation trajectory– and how different cell types control those trajectories. We take a protein energy landscape view of protein folding and misfolding and use systems genetics techniques to gain a comprehensive view of how cells control protein aggregation trajectories.
We are part of the UCLA David Geffen School of Medicine Department of Neurology with a secondary affiliation in the Department of Biological Chemistry.
Avi Samelson, Ph.D.
Assistant Professor
Department of Neurology
Department of Biological Chemistry
email: avi.samelson (at) ucsf.edu
MRL 5-768 (Office), 5-619 (Lab)
675 Charles E. Young Dr. South
Los Angeles, CA 90095